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Zyflamend: Pain Relief Support Zyflamend: Pain Relief Support

Complement your multivitamin with Zyflamend, our premier multi-herbal supplement and the #1 natural joint supplement† to support pain relief and healthy inflammation response.*†

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Bone, Joint & Mobility (2)

Beauty & Healthy Aging (1)

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4 products

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Inflammation Support

Zyflamend™: Herbal Pain Relief† & Inflammation Support†Sale priceFrom $34.00

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Zyflamend™ NighttimeSale price $34.00

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Zyflamend™ ProstateSale price $37.00

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Inflammation Support

Zyflamend™ Mini SoftgelsSale price $46.00

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Supplements for Pain Relief FAQ

What are supplements that help with pain relief?

Supplements that support pain relief include ginger that works with your body’s inflammation response.* A plant-based pain relief supplement can deliver a combination of time-tested herbs to promote whole-body wellness.* These formulas are suitable for daily use.*

What is Zyflamend?

Zyflamend is New Chapter’s premier herbal combo. This beloved formula features 10 traditional superfood herbs from around the world. Originally launched as “Inflamend" in 1999, this product was also formerly called Zyflamend Whole Body. It’s New Chapter’s #1 natural joint supplement.†

†Leading item in Natural Joint Supplement category based on total Natural Channel $ sales in the latest 52 weeks through 5/17/26.

How does Zyflamend help with joint health & healthy inflammation response?

Zyflamend is the #1 natural joint & muscle pain reliever.§ Zyflamend is an herbal approach to pain relief.**† Zyflamend helps you stay active by supporting a natural, healthy inflammation response, and by supporting healthy joint function, mobility, and flexibility.**† And it works hard—Zyflamend’s 10 powerful herbs are actually proven to work better together as a blend compared with testing each herb separately.*‡

Works on pain where it can start, delivering potent Ginger to help relieve minor pain or soreness*†
10 herb blend proven to work better together—including synergistic whole herbs like Turmeric & Ginger*‡
Formulated with supercritical Turmeric for optimal absorption of Curcumin

† With Ginger for occasional pain relief and healthy inflammation response after exercise

‡ As shown in preclinical studies

§Leading item in the Natural Joint and Muscle Pain Reliever category based on total AMZ $ sales in the latest 52 weeks through 5/30/26

What makes New Chapter Zyflamend different?

Many people seeking joint support take glucosamine or chondroitin. While these supplements are popular for joint support, they only affect joint structure. Zyflamend works on pain where it can start—at the cellular level.† It’s a clinically studied 10-herb blend expertly formulated to support your whole body’s healthy response to inflammation, which in turn supports joint comfort and movement.*†

Pure & potent 10-in-1 superfood blend
Purely herbal pain relief*†
Supports healthy mobility, flexibility, joint function, and healthy inflammation response*†
Sustainably sourced and Non-GMO Project Verified
No synthetic fillers, harsh Solvents, DLPA, or animal enzymes and byproducts, no artificial preservatives

Who is the Zyflamend supplement for?

Anyone interested in supporting an active, mobile lifestyle can enjoy Zyflamend’s multiple benefits! Whether you’re a marathoner, dancer, walker, swimmer, gym shark, hiker, or chasing your grandkids, Zyflamend can support comfortable, flexible movement by supporting your joints and balancing inflammation.*†

Learn more about [Zyflamend’s history and benefits](/content/wellness-blog/what-is-in-zyflamend/ "History of Zyflamend"/index.html) on our blog!

Reviews Reviews

Spoo1971, newchapter.com review

Zyflamend

"I started using Zyflamend several years ago to help relieve exercise-related soreness. After my husband saw how much it helped me he became a regular user as well. We’re so grateful for the effectiveness of this product."

stinedog, newchapter.com review (received free product)

Zyflamend

"I love Zyflamend, I have been using it regularly for about a year now and I can certainly feel a difference. It is easier to move, my joints feel much better. This was a good addition to my supplement routine."

Mysto Mark, newchapter.com review

Zyflamend

"I am a daily user of Zyflamend. Helps me stay active at 50 years old! Keeping up with kids half my age. Soreness is not an issue. Notice the biggest difference when I run out. Soreness and inflammation come back..."

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